منابع مشابه
Optic pathway gliomas.
BACKGROUND Childhood optic pathway gliomas (OPGs) are low-grade neoplasms intrinsic to the optic nerve, optic chiasm, tracts, and radiations. The management of OPGs is still a highly controversial topic among neuro-ophthalmologists. EVIDENCE ACQUISITION Authors' personal experience and literature review. RESULTS This review describes our current understanding of the behavior of OPGs and dis...
متن کاملOptic pathway gliomas: neoplasms, not hamartomas.
IMPORTANCE Optic pathway gliomas are an important neuro-ophthalmic cause of vision loss in children. Their management depends on whether they are considered neoplasms or hamartomas. OBJECTIVE To outline the evidence that optic pathway gliomas are slowly growing neoplasms and not hamartomas. DESIGN Review of relevant studies in the literature. SETTING The authors are from a pediatric terti...
متن کاملManagement of optic nerve gliomas.
Seventeen patients thought to have orbital optic nerve gliomas when first seen have been reviewed after up to 12 years. Enlargement of the optic canal was present in 15 of the 16 patients examined, but this finding was unreliable as an indicator of the posterior extent of the tumour. Nine patients had a stable course with little change over a period of up to 8 years; there was optic atrophy in ...
متن کاملFractional anisotropy of the optic radiations is associated with visual acuity loss in optic pathway gliomas of neurofibromatosis type 1.
BACKGROUND No more than half of patients with neurofibromatosis type 1 (NF1)-associated optic pathway gliomas (OPGs) develop vision loss. Prospectively identifying those who will require therapy remains challenging, because no reliable factors have yet been identified that predict future vision loss. To determine whether brain tissue microstructure is associated with visual acuity loss, we exam...
متن کاملNeurofibromatosis type 1 and sporadic optic gliomas.
AIMS To compare the natural history of sporadic optic glioma with those associated with neurofibromatosis type 1 (NF1). METHODS Optic glioma cases were identified using both the Manchester Children's Tumour Registry (CTR) and the North West Regional NF1 Database (NF1DB), with detailed information on natural history available from the former (in 34 of 36 cases identified). RESULTS A total of...
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ژورنال
عنوان ژورنال: JAMA Ophthalmology
سال: 2013
ISSN: 2168-6165
DOI: 10.1001/jamaophthalmol.2013.1652